Magnesium sulphate for women at risk of preterm birth for neuroprotection of the fetus

ES Shepherd, S Goldsmith, LW Doyle… - Cochrane Database …, 2024 - cochranelibrary.com
Cochrane Database of Systematic Reviews, 2024cochranelibrary.com
Background Magnesium sulphate is a common therapy in perinatal care. Its benefits when
given to women at risk of preterm birth for fetal neuroprotection (prevention of cerebral palsy
for children) were shown in a 2009 Cochrane review. Internationally, use of magnesium
sulphate for preterm cerebral palsy prevention is now recommended practice. As new
randomised controlled trials (RCTs) and longer‐term follow‐up of prior RCTs have since
been conducted, this review updates the previously published version. Objectives To assess …
Abstract
Background
Magnesium sulphate is a common therapy in perinatal care. Its benefits when given to women at risk of preterm birth for fetal neuroprotection (prevention of cerebral palsy for children) were shown in a 2009 Cochrane review. Internationally, use of magnesium sulphate for preterm cerebral palsy prevention is now recommended practice. As new randomised controlled trials (RCTs) and longer‐term follow‐up of prior RCTs have since been conducted, this review updates the previously published version.
Objectives
To assess the effectiveness and safety of magnesium sulphate as a fetal neuroprotective agent when given to women considered to be at risk of preterm birth.
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